Phospho-Abl1/2 (Y393/439) Polyclonal Antibody, 100ul[BT-PHS00619] Modification Enzymes exons 2 and 3 encode

exons 2 and 3 encode the alpha1 and alpha2 domains

2 may function as a tumor suppressor

One of the transcripts produced from this locus| and the antisense transcript| are paternally expressed noncoding RNAs| and may regulate imprinting in this region

The encoded protein is thought to be involved in stereocilia organization and hair bundle formation

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Phospho-Abl1/2 (Y393/439) Polyclonal Antibody, 100ul[BT-PHS00619] Modification Enzymes exons 2 and 3 encodeABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation, suggesting a